毒素T3DB ID

T3D0166

目标BioDB ID

BE0003721

目标名称

Aryl hydrocarbon receptor

目标UniProt ID

P35869

作用机理

Dibenzofurans bind the aryl hydrocarbon receptor, which increases its ability to activate transcription in the XRE promoter region. This alters the expression of a number of genes. (A586)

参考文献

A586 - Ni J, Pang ST, Yeh S: Differential retention of alpha-vitamin E is correlated with its transporter gene expression and growth inhibition efficacy in prostate cancer cells. Prostate. 2007 Apr 1;67(5):463-71. (17252538) T148 - Long G, McKinney J, Pedersen L. Polychlorinated Dibenzofuran (PCDF) Binding to the Ah Receptor(s) and Associated Enzyme Induction. Theoretical Model Based on Molecular Parameters. Quantitative Structure-Activity Relationships. 2002;6(1):1-7.

创建于

2009-07-02 20:09:53 UTC

更新于

2014-09-04 16:10:52 UTC

目标详情