毒素T3DB ID

T3D0170

目标BioDB ID

BE0001075

目标名称

Myeloperoxidase

目标UniProt ID

P05164

作用机理

p-Cresol binds near the heme center of myeloperoxidase. (A202)

参考文献

A202 - Hori H, Fenna RE, Kimura S, Ikeda-Saito M: Aromatic substrate molecules bind at the distal heme pocket of myeloperoxidase. J Biol Chem. 1994 Mar 18;269(11):8388-92. (8132563) A7868 - Schulz AM, Terne C, Jankowski V, Cohen G, Schaefer M, Boehringer F, Tepel M, Kunkel D, Zidek W, Jankowski J: Modulation of NADPH oxidase activity by known uraemic retention solutes. Eur J Clin Invest. 2014 Aug;44(8):802-11. doi: 10.1111/eci.12297. (25041433) A7869 - Young GH, Wu VC: KLOTHO methylation is linked to uremic toxins and chronic kidney disease. Kidney Int. 2012 Apr;81(7):611-2. doi: 10.1038/ki.2011.461. (22419041)

创建于

2009-06-05 20:52:22 UTC

更新于

2014-09-04 16:17:52 UTC

目标详情