毒素T3DB ID

T3D0170

目标BioDB ID

BE0000138

目标名称

Dopamine beta-hydroxylase

目标UniProt ID

P09172

作用机理

p-Cresol inhibits dopamine beta-hydroxylase. (A199)

参考文献

A199 - Kruse LI, DeWolf WE Jr, Chambers PA, Goodhart PJ: Design and kinetic characterization of multisubstrate inhibitors of dopamine beta-hydroxylase. Biochemistry. 1986 Nov 18;25(23):7271-8. (3801416) A7868 - Schulz AM, Terne C, Jankowski V, Cohen G, Schaefer M, Boehringer F, Tepel M, Kunkel D, Zidek W, Jankowski J: Modulation of NADPH oxidase activity by known uraemic retention solutes. Eur J Clin Invest. 2014 Aug;44(8):802-11. doi: 10.1111/eci.12297. (25041433) A7869 - Young GH, Wu VC: KLOTHO methylation is linked to uremic toxins and chronic kidney disease. Kidney Int. 2012 Apr;81(7):611-2. doi: 10.1038/ki.2011.461. (22419041)

创建于

2009-06-05 18:10:06 UTC

更新于

2014-09-04 16:19:04 UTC

目标详情