当前位置：药药网 / 数据中心 / 毒素靶向作用机制
Chlorpyrifos
目标名称
Acetylcholinesterase
作用机理
Chlorpyrifos and its bioactivation product, chlorpyrifos oxon, and inhibit neural acetylcholinesterase by forming a stable covalent bond at the active site. The result of this acetylcholinesterase inhibition is cholinergic overstimulation of the central nervous system. (L268)
参考文献
L268 - ATSDR - Agency for Toxic Substances and Disease Registry (1997). Toxicological profile for chlorpyrifos. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp84.html)
创建于
2009-05-28 20:29:07 UTC
更新于
2014-09-04 16:14:03 UTC