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Vinyl chloride
作用机理
The metabolites of vinyl chloride, especially choloroethylene oxide, are mutagenic and act by covalently binding to DNA. This produces cyclic etheno-adducts, which cause base-pair transitions during transcription and DNA crosslinks. (L3)
参考文献
L3 - ATSDR - Agency for Toxic Substances and Disease Registry (2006). Toxicological profile for vinyl chloride. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp20.html)
创建于
2009-05-26 20:02:57 UTC
更新于
2014-09-29 19:30:27 UTC