毒素T3DB ID

T3D0089

目标BioDB ID

BE0005186

目标名称

Sodium/iodide cotransporter

目标UniProt ID

Q92911

作用机理

Thiocyanate is a competitive inhibitor of the human thyroid sodium/iodide symporter NIS, which plays an important role in moving thiocyanate ions into epithelial cells. (A140, A143)

参考文献

A140 - Laurberg P, Nohr SB, Pedersen KM, Fuglsang E: Iodine nutrition in breast-fed infants is impaired by maternal smoking. J Clin Endocrinol Metab. 2004 Jan;89(1):181-7. (14715847) A143 - Taga I, Oumbe VA, Johns R, Zaidi MA, Yonkeu JN, Altosaar I: Youth of west-Cameroon are at high risk of developing IDD due to low dietary iodine and high dietary thiocyanate. Afr Health Sci. 2008 Sep;8(3):180-5. (19357747)

创建于

2009-05-26 06:10:17 UTC

更新于

2014-09-04 16:17:52 UTC

目标详情