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1,2-Dibromo-3-chloropropane
目标名称
NADH-ubiquinone oxidoreductase chain 2
作用机理
Inhibition of sperm carbohydrate metabolism at the step of nicotinamide adenine dinucleotide (NADH) dehydrogenase activity in the mitochondrial electron transport chain is a factor of 1,2-dibromo-3-chloropropane's testicular toxicity.
参考文献
A13 - Greenwell A, Tomaszewski KE, Melnick RL: A biochemical basis for 1,2-dibromo-3-chloropropane-induced male infertility: inhibition of sperm mitochondrial electron transport activity. Toxicol Appl Pharmacol. 1987 Nov;91(2):274-80. (3672526)
创建于
2009-05-11 23:55:24 UTC
更新于
2014-09-04 16:14:18 UTC