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3,3'-Dichlorobenzidine
目标名称
Aryl hydrocarbon receptor
作用机理
3,3鈥?Dichlorobenzidine acts on the aryl hydrocarbon receptor to induce the activity of cytochrome p-450 enzymes, which metabolize 3,3鈥?dichlorobenzidine, along with other polyhalogenated aromatics, into their toxic intermediates. (A90)
参考文献
A90 - Cikryt P, Josephy PD: Binding of chlorinated benzidines to the rat hepatic aromatic hydrocarbon receptor. Chem Biol Interact. 1989;72(1-2):57-64. (2555073)
创建于
2009-05-08 18:02:51 UTC
更新于
2014-09-04 16:10:38 UTC