毒素T3DB ID

T3D0037

目标BioDB ID

BE0001122

目标名称

Transient receptor potential cation channel subfamily A member 1

目标UniProt ID

O75762

作用机理

Acrolein activates the transient receptor potential cation channel, causing acute pain. (A87)

参考文献

A87 - Takahashi N, Mizuno Y, Kozai D, Yamamoto S, Kiyonaka S, Shibata T, Uchida K, Mori Y: Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators. Channels (Austin). 2008 Jul-Aug;2(4):287-98. Epub 2008 Jul 6. (18769139) A15110 - Nilius B, Prenen J, Owsianik G: Irritating channels: the case of TRPA1. J Physiol. 2011 Apr 1;589(Pt 7):1543-9. doi: 10.1113/jphysiol.2010.200717. Epub 2010 Nov 15. (21078588)

创建于

2009-05-07 22:29:19 UTC

更新于

2014-09-04 16:14:10 UTC

目标详情