毒素T3DB ID

T3D0037

目标BioDB ID

BE0000554

目标名称

Retinal dehydrogenase 1

目标UniProt ID

P00352

作用机理

Acrolein inhibits aldehyde dehydrogenases. (A85)

参考文献

A85 - Bunting KD, Townsend AJ: Dependence of aldehyde dehydrogenase-mediated oxazaphosphorine resistance on soluble thiols: importance of thiol interactions with the secondary metabolite acrolein. Biochem Pharmacol. 1998 Jul 1;56(1):31-9. (9698086) A9688 - Yoval-Sanchez B, Rodriguez-Zavala JS: Differences in susceptibility to inactivation of human aldehyde dehydrogenases by lipid peroxidation byproducts. Chem Res Toxicol. 2012 Mar 19;25(3):722-9. doi: 10.1021/tx2005184. Epub 2012 Feb 29. (22339434)

创建于

2009-05-07 22:18:25 UTC

更新于

2014-09-04 16:14:06 UTC

目标详情