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Acrolein
目标名称
Inhibitor of nuclear factor kappa-B kinase subunit beta
作用机理
Perturbation of inflammatory responses in bronchial epithelial cells was demonstrated by direct action of acrolein on the inhibitor of nuclear factor kappa-B (I魏B) kinase, which inhibits activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-魏B) transcription factor and suppresses interleukin 8 (IL-8) production. (A83)
参考文献
A83 - Kaphalia BS, Ansari GA: Covalent binding of ethylene dibromide and its metabolites to albumin. Toxicol Lett. 1992 Sep;62(2-3):221-30. (1412507)
创建于
2009-05-07 21:27:02 UTC
更新于
2014-09-04 16:14:05 UTC