当前位置：药药网 / 数据中心 / 毒素靶向作用机制
2,4-Dinitrotoluene
目标名称
Hemoglobin subunit alpha
作用机理
Dinitrotoluene may cause conversion of oxyhemoglobin to methemoglobin via oxidation of iron(II) to iron(III) by its metabolites. High levels of methemoglobin are removed by catabolism, leading to the development of anemia. (L276)
参考文献
L276 - ATSDR - Agency for Toxic Substances and Disease Registry (1998). Toxicological profile for 2,4-,and 2,6-dinitrotoluene. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp109.html)
创建于
2009-08-06 21:43:10 UTC
更新于
2014-09-04 15:56:32 UTC