毒素T3DB ID

T3D0123

目标BioDB ID

BE0003400

目标名称

Tubulin beta-2A chain

目标UniProt ID

Q13885

作用机理

Organic mercury exerts developmental effects by binding to tubulin, preventing microtubule assembly and causing mitotic inhibition. (L7)

参考文献

A15095 - Vogel DG, Margolis RL, Mottet NK. "The effects of methyl mercury binding to microtubules". Toxicol Appl Pharmacol. 1985 Sep 30;80(3):473-86. (4035699) L7 - ATSDR - Agency for Toxic Substances and Disease Registry (2008). Toxicological profile for mercury. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp46.html)

创建于

2009-04-14 21:08:39 UTC

更新于

2014-09-04 16:11:38 UTC

目标详情