毒素T3DB ID

T3D0074

目标BioDB ID

BE0002390

目标名称

Superoxide dismutase [Cu-Zn]

目标UniProt ID

P00441

作用机理

Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). (A49)

参考文献

A49 - Vonk WI, Klomp LW: Role of transition metals in the pathogenesis of amyotrophic lateral sclerosis. Biochem Soc Trans. 2008 Dec;36(Pt 6):1322-8. doi: 10.1042/BST0361322. (19021549) A10094 - Huang YH, Shih CM, Huang CJ, Lin CM, Chou CM, Tsai ML, Liu TP, Chiu JF, Chen CT: Effects of cadmium on structure and enzymatic activity of Cu,Zn-SOD and oxidative status in neural cells. J Cell Biochem. 2006 Jun 1;98(3):577-89. (16440303)

创建于

2009-04-14 21:08:39 UTC

更新于

2014-09-04 16:11:05 UTC

目标详情