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Benzocaine
目标名称
Sodium channel protein type 10 subunit alpha
作用机理
Benzocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.
参考文献
A358 - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. (17139284)
A359 - Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. (17016423)
创建于
2009-07-22 22:37:15 UTC
更新于
2014-09-04 16:15:39 UTC