当前位置:药药网 / 数据中心 / 毒素靶向作用机制
Gatifloxacin
目标名称
DNA topoisomerase 2-alpha
作用机理
The bactericidal action of Gatifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.
参考文献
A365 - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. (11752352)
创建于
2009-07-22 22:37:11 UTC
更新于
2014-09-04 16:09:46 UTC