毒素T3DB ID

T3D2968

目标BioDB ID

BE0000530

目标名称

Serum albumin

目标UniProt ID

P02768

作用机理

The bactericidal action of Gatifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.

参考文献

A2032 - Guo M, Zou JW, Yi PG, Shang ZC, Hu GX, Yu QS: Binding interaction of gatifloxacin with bovine serum albumin. Anal Sci. 2004 Mar;20(3):465-70. (15068289) A2033 - Tan F, Guo M, Yu Q: Studies on interaction between gatifloxacin and human serum albumin as well as effect of copper(II) on the reaction. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Oct;61(13-14):3006-12. Epub 2004 Dec 19. (16165044)

创建于

2009-07-22 22:37:11 UTC

更新于

2014-09-04 16:12:46 UTC

目标详情