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Toxaphene
目标名称
Estrogen receptor alpha
作用机理
Causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (A590)
参考文献
A59 - Lemaire G, Mnif W, Mauvais P, Balaguer P, Rahmani R: Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines. Life Sci. 2006 Aug 15;79(12):1160-9. Epub 2006 Mar 27. (16626760)
A590 - Taccone-Gallucci M, Manca-di-Villahermosa S, Battistini L, Stuffler RG, Tedesco M, Maccarrone M: N-3 PUFAs reduce oxidative stress in ESRD patients on maintenance HD by inhibiting 5-lipoxygenase activity. Kidney Int. 2006 Apr;69(8):1450-4. (16531984)
A9669 - Hodges LC, Bergerson JS, Hunter DS, Walker CL: Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro. Toxicol Sci. 2000 Apr;54(2):355-64. (10774817)
A10057 - Chen S, Zhou D, Yang C, Sherman M: Molecular basis for the constitutive activity of estrogen-related receptor alpha-1. J Biol Chem. 2001 Jul 27;276(30):28465-70. Epub 2001 May 16. (11356845)
T152 - Luft S, Milki E, Glustrom E, Ampiah-Bonney R, O'Hara P. Binding of Organochloride and Pyrethroid Pesticides To Estrogen Receptors 伪 and 尾: A Fluorescence Polarization Assay. Biophysical Journal 2009;96(3):444a.
创建于
2009-04-14 21:08:37 UTC
更新于
2014-09-04 15:56:33 UTC