毒素T3DB ID

T3D0025

目标BioDB ID

BE0000132

目标名称

Androgen receptor

目标UniProt ID

P10275

作用机理

DDD is also believed to adversely affect the reproductive system by mimicking endogenous hormones and binding to the estrogen and adrogen receptors. (L85)

参考文献

A9887 - Yamasaki K, Sawaki M, Noda S, Muroi T, Takakura S, Mitoma H, Sakamoto S, Nakai M, Yakabe Y: Comparison of the Hershberger assay and androgen receptor binding assay of twelve chemicals. Toxicology. 2004 Feb 15;195(2-3):177-86. (14751673) L85 - ATSDR - Agency for Toxic Substances and Disease Registry (2005). Toxicological profile for DDT, DDE, and DDD. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp35.html)

创建于

2009-04-14 21:08:36 UTC

更新于

2014-09-04 16:05:37 UTC

目标详情