毒素T3DB ID

T3D0020

目标BioDB ID

BE0000206

目标名称

Retinoic acid receptor beta

目标UniProt ID

P10826

作用机理

Chlordane has been shown to bind and activate retinoic acid receptor, causing various developmental defects. (A53)

参考文献

A53 - Lemaire G, Balaguer P, Michel S, Rahmani R: Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides. Toxicol Appl Pharmacol. 2005 Jan 1;202(1):38-49. (15589975) A15114 - Sipes NS, Martin MT, Kothiya P, Reif DM, Judson RS, Richard AM, Houck KA, Dix DJ, Kavlock RJ, Knudsen TB: Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays. Chem Res Toxicol. 2013 Jun 17;26(6):878-95. doi: 10.1021/tx400021f. Epub 2013 May 16. (23611293)

创建于

2009-04-14 21:08:36 UTC

更新于

2014-09-04 16:08:21 UTC

目标详情