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Hexavalent chromium
目标名称
Mitogen-activated protein kinase 3
作用机理
Chromium has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. (A34)
参考文献
A34 - Kim G, Yurkow EJ: Chromium induces a persistent activation of mitogen-activated protein kinases by a redox-sensitive mechanism in H4 rat hepatoma cells. Cancer Res. 1996 May 1;56(9):2045-51. (8616849)
创建于
2009-04-14 21:08:36 UTC
更新于
2014-09-04 16:07:43 UTC