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Lead
目标名称
Protein kinase C gamma type
作用机理
Lead exhibits competitive inhibition with calcium at protein kinase C, which impairs brain microvascular formation and function, as well as alters the blood-brain barrier. (L136)
参考文献
L136 - ATSDR - Agency for Toxic Substances and Disease Registry (2007). Toxicological profile for lead. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp13.html)
创建于
2009-04-14 21:08:35 UTC
更新于
2014-09-04 16:06:22 UTC