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Dichloromethane
目标名称
Hemoglobin subunit gamma-2
作用机理
Methylene chloride is metabolized into carbon monoxide, which binds to hemoglobin to produce dose-dependent increases in carboxyhemoglobin. This results in the reduced oxygen transport and neurological dysfunction characteristic of carboxyhemoglobinemia (carbon monoxide poisoning). (L188)
参考文献
L188 - ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for methylene chloride. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp14.html)
创建于
2009-05-22 21:46:04 UTC
更新于
2014-09-04 16:07:46 UTC