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Dimethylarsinate
目标名称
Tubulin epsilon chain
作用机理
Arsenic's carginogenicity is believed to be caused by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. (A17)
参考文献
A17 - Kitchin KT, Wallace K: The role of protein binding of trivalent arsenicals in arsenic carcinogenesis and toxicity. J Inorg Biochem. 2008 Mar;102(3):532-9. doi: 10.1016/j.jinorgbio.2007.10.021. Epub 2007 Nov 22. (18164070)
创建于
2009-05-21 19:12:36 UTC
更新于
2014-09-04 16:08:26 UTC