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2-Oxohexane
目标名称
Glyceraldehyde-3-phosphate dehydrogenase
作用机理
2-Hexanone and 2,5-hexanedione may inhibit sulfhydryl-dependent enzymes such as glyceraldehyde-3-phosphate dehydrogenase , impairing energy metabolism and subsequently resulting in axon deterioration. (A124)
参考文献
A124 - Couri D, Milks M: Toxicity and metabolism of the neurotoxic hexacarbons n-hexane, 2-hexanone, and 2,5-hexanedione. Annu Rev Pharmacol Toxicol. 1982;22:145-66. (7044283)
创建于
2009-05-21 15:47:56 UTC
更新于
2014-09-04 16:17:48 UTC