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 药品生产,药物连续结晶手册 786条(本栏目收费,不能显示细节,电话13136136841)
microwave fields,304,305 305
ultrasound,298,302 302
function domain,282,283 283
hybrid processes,283,291 291
screening and phase diagram,374,377 377
transition from batch,381 381
protein crystals,373 373
proteins downstream processing of,372,373 373
continuous seeding,29,30 30
continuous stirred tank reactors(CSTRs),105 105
cooling,53 53
cooling crystallization,17,119 119
seeded cases,124,125 125
unseeded cases,123,124 124
counter current cooling crystallization (CCCC crystallizer),410,411 411
CQAs. See critical quality attributes critical process parameters (CPPs),187 187
critical quality attributes (CQAs),187 187
crystal habit,175 175
crystal nucleation,2,4 4
primary nucleation,4,5 5
electric or magnetic fields,10 10
external fields,7,10 10
laser-induced nucleation,9,10 10
mixing-induced supersaturation,5,6 6
shear,6,7 7
ultrasound-induced nucleation,8,9 9
secondary nucleation attrition fragmentation breakage,12,16 16
seeded crystallization,11,12 12
crystal size distribution (CSD),175,398 398
crystalline excipient surface,21,26 26
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