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 药物设计与发现 1119条(本栏目收费,不能显示细节,电话13136136841)
chlortetracycline, 422 422
glycylcyclines, 422 422
octahydronaphthacene, 422 422
semisynthetic, 422–423 423
tigecycline, 423 423
Tetraed test, 338 338
Thapsigargin, 6–7 7
Topological polar surface area (TPSA), 62–63 63
Transient receptor potential (TRP) cation channels,218, 222 222
Transporter ligands 0
antidepressant drugs, 316 316
discovery of citalopram 0
neuronal test models, 319 319
phenylphthalane antidepressants., 317–318 318
SAR, 319 319
treatment of MDD, 320 320
escitalopram, 320 320
first-generation drugs, 316 316
pharmacotherapy of depression, 316 316
selective serotonin reuptake inhibitors, 317,319, 321 321
SSRIs, 321 321
Transport mechanisms, 195, 236 236
Tricyclic antidepressants (TCAs), 244–245, 297 297
antibiotics inhibiting DNA gyrase, 419–420 420
antibiotics inhibiting RNA polymerase (RNAP),418–419 419
Nucleoside and nucleotide RT inhibitors (NRTIs), 180–181 181
Opioid receptors 0
description, 329 329
endogenous ligands, 330, 332–333 333
ligands, 330, 332 332
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