抗生素耐药性 1008条(本栏目收费,不能显示细节,电话13136136841)
effect of antibiotic‐induced alterations 21–23 23
reservoir of antibiotic resistance 24–25 25
strategies to modulate human microbiome 25–26 26
mechanisms of action 8–10 10
mechanisms of resistance aminoglycoside‐modifying enzymes 10–13 13
changes in uptake and efflux 14–16 16
aminoglycosides/aminoglycoside antibiotics (AGAs) (cont’d) mutation/modification of ribosomal target sequences 13–14 14
potential of glycomics 16 16
carbohydrate chemistry 17–18 18
second‐generation AGAs 5 5
aminoglycoside‐terminated hyperbranched polyaminoglycosides 424 424
6‐aminopenicillanic acid (6‐APA) 59 59
aminopenicillins 60–61 61
amoxicillin (AMO) 424 424
amphiphilic tobramycin (TOB) 466 466
mechanism of action 508,513–514 514
consequences and future strategies 250–251 251
contaminant resistome 215–216 216
Escherichia coli 243–244 244
evolution of antibiotics usage 216–219 219
extended‐spectrum β‐lactamase 247–250 250
final considerations 227 227