发现抗病毒药物的成功策略 1559条(本栏目收费,不能显示细节,电话15274084725)
immunosuppressive/nonimmunosuppressive derivatives 389,390 390
modification to treat viral diseases 395,404 404
structure/conformational flexibility 387,388,395 395
cytochrome P450 enzymes (CYPs) 430,431 431
cobicistat inhibition 469 469
CYP-mediated oxidation 2-fluorophenyl rings 281 281
CYP2D6 inhibition 266,267 267
inhibitors cobicistat 156 156
ritonavir 457,458,460 460
CYP3A4 subfamily induction 267 267
CYP3A4,ritonavir complex 462 462
CYP450-dependent/-independent processes 436,438 438
drug,drug interactions 476 476
induction 120,121,267 267
STARTMRK phase 3 trial 155 155
CM2 protein of influenza C 318 318
CMX001 acyclic nucleoside 99
phosphonate analog 91,95,99 99
cobicistat (COBI,GS-9350) 156,466,473 473
enhancer for anti-HIV agents 471,473 473
EVG/COBI/FTC/7340 483,484,504 504
EVG/COBI/FTC/TDF 483,484,495,503,504 504