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 药物开发过程:提高效率和成本效益 328条(本栏目收费,不能显示细节,电话13136136841)
Oral osmotic pumps (OROS), 175 175 
Orphan Drug Act, 62-63 62 63 
Patent and Trademark Office (PTO), 61 61 
Pharmaceutical industry changes in, 39-44 39 44 
Pharmacodynamics, 23 23 
Pharmacognosy, 5 5 
Pharmacy benefit management companies (PBMs), 64 64 
Programmed electrical stimulation (PES), 23 23 
Pharmacokinetically guided dose escalations (PGDE), 288 288 
Pharmacokinetic/pharmacodynamic relationship, 23 23 
Pharmacokinetics, 23, 262-264 23  262 264 
studies, 266-277 266 277 
Physiological systems modeling, 241-244 241 244 
mathematical, 242 242 
Portfolio analysis, 101-114 101 114 
criteria for, 103-104 103 104 
interpretation of, 112-114 112 114 
complications, 101-103 101 103 
considerations, 101-103 101 103 
development, 106-107 106 107 
discovery, 104-106 104 106 
quantitative assessment of, 107-109 107 109 
research and development, 101-114 101 114 
review, 109-112 109 112 
Positron emission tomography (PET), 248 248 
Powdered cellulose, 122 122 
Preclinical studies, 220-252 220 252 
Pregelatinized starch, 123 123 
Prescription Drug User Fee Act of 1992, 59 59 
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