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药物开发过程:提高效率和成本效益 328条(本栏目收费,不能显示细节,电话13136136841)
support of Phase II and III trials, 395-400
395 400
testing in Europe, 379-420
379 420
Clinical pharmacology, 267-270, 296
267 270 296
Clinical trials, 10, 32
10 32
Compressible sugar, 122
122
Computer-aided drug design (CADD), 204-215
204 215
drug discovery, 209-210
209 210
Computer assisted product license applications (CAPLAs), 437, 438
437 438
Computer Optimized Parametric Analysis of Chemical Toxicity (COMPACT), 223
223
Concentration dose, 21
21
Continuous reassessment method (CRM), 288
288
Contract Research Organization (CRO), 13, 14, 84, 317-334, 340-351
13 14 84 317 334 340 351
disadvantages of, 322-323
322 323
evaluating the need for, 323
323
factors affecting success with, 345
345
process of contracting out to, 323-326
323 326
project implementation with, 346-351
346 351
rationale for using, 343-344
343 344