新型冠状病毒2019硅疫苗设计与药物发现 67条(本栏目收费,不能显示细节,电话13136136841)
4.6 3D Structure Visualization of the SARS Corona Virus 2 RNA-Dependent RNA Polymerase Protein in RASMOL...... 33 33
4.7 Prediction of Disordered Sites Within the Protein Structure Based on GLOBPLOT........ 34 34
5 Rational Drug Design and Docking of the RNA Dependent RNA Polymerase Domain of NCoV....... 37 37
5.1 Selection Criteria for Chemicals............. 38 38
5.2 Docking of the Chemicals in HEX........... 39 39
5.3 Docking Results Summarized.............. 40 40
6 Herbal Treatment Approach Towards COVID19... 47 47
6.1 Some of the Medicinal Plants in the COVID Therapy........ 47 47
6.2 Zingiber Officinale/Ginger...... 47 47
6.3 Allium Sativum/Garlic........ 49 49
6.4 Tinospora Cordifolia/Giloy................ 49 49
6.5 Ocimum Tenuiflorum/Tulsi and Withania Somnifera/Ashwaganda........ 50 50
7 Evolutionary and Structural Studies of NCoV and SARS CoV-Spike proteins and their association with ACE2 Receptor... 53 53
7.1 Introduction......... 53 53
7.2 Materials and Methods........ 55 55
7.2.1 Collection of Sequences............. 55 55
7.2.2 Phylogenetic Analysis.............. 55 55
7.2.3 Protein Structure Homology Modeling by ITASSER... 55 55
7.2.4 Protein-Protein Docking............. 55 55
7.2.5 Structural and Functional Analysis of NCoV 19 and SARS-CoV Using Human ACE2... 56 56
7.3 Results............. 56 56
7.4 Discussion.......... 59 59
7.5 Conclusion.......... 60 60
8 Plasma Therapy Towards COVID Treatment...... 63 63
8.1 Assessing Global Success Rate of Plasma Therapy.......... 64 64
8.2 Plasma Therapy Guidelines and Significance in India........ 64 64