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药物发现和开发的基本原则 1336条(本栏目收费,不能显示细节,电话13136136841)
apolipoprotein E-deficient (apoE−/− ) mouse model, 326–327, 326f
326 327 326
atrial fibrillation (AF) normal sinus rhythm, 327, 327f
327 327
sterile pericarditis dog model, 328,328f
328 328
hypercholesterolemia, diet-induced
characteristics and impact, 421–422
421 422
diagnostic biomarkers, 420–421
420 421
DPP-IV inhibitors (Januvia®), 432–434,433f
432 434 433
FDG PET imaging agent, 436–437
436 437
imaging agents and technologies
[18F] fluororasagiline, 428–429, 429f
428 429 429
[18F] fluororeboxetine, 429, 429f
429 429
functional magnetic resonance
human chorionic gonadotropin (hCG),424
424
L-829,165-18F, 438f, 439 165-18, 438, 439
magnetic resonance imaging (MRI),430–431
430 431
neurokinin 1 (NK1), 438–439
438 439
non-specific binding, 429–430
429 430
positron emission tomography (PET),426–427, 427t
426 427 427
selective orexin receptor antagonists,436
436
single-photon emission computed
Electrophysiological patch clamp, 191–193,192f–193f
191 193 192 193
Elixir of Sulfanilamide disaster, 69–71, 69f
69 71 69
Endocytosis, 255, 255f
255 255