“咖啡因”、“氯甲酚”、“氟烷”-"caffeine","chlorocresol","halothane"
注释ID
1447521586
变量_单倍型
rs121918594
基因
RYR1
药物名称(英)
"caffeine","chlorocresol","halothane"
药物名称(中)
“咖啡因”、“氯甲酚”、“氟烷”
PMID
22415532
类型
Other
含义
yes
记事
The A allele is designated as MHS causative by the European Malignant Hyperthermia Group. The authors of the study tested whether this variant confers MHS characteristics using differentiated skeletal muscle cells from MHS and MH negative (MHN) controls by assaying cells with chlorocrasol, halothane, and caffeine.
专家论述
Allele A is associated with increased sensitivity to caffeine, chlorocresol or halothane in differentiated muscle cells as compared to allele G.
等位基因
A
专家评论
变体注释摘要
id研究类型特征类型
26827 Drug
26826 Drug
26825 Drug
26824 Disease
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