当前位置：药药网 / 数据中心 /变体注释摘要_体外和功能分析类型
布呋洛尔-bufuralol
变量_单倍型
CYP2D6*1, CYP2D6*92, CYP2D6*96
记事
CYP2D6.92 (construct containing 218 frameshift) and CYP2D6.96 (construct containing 424X) exhibited no detectable enzymatic activity toward bufuralol.
专家论述
CYP2D6 *92 + *96 are associated with decreased catalytic activity of CYP2D6 when assayed with bufuralol in insect microsomes as compared to CYP2D6 *1.