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变量_单倍型
CYP2D6*1, CYP2D6*92
记事
CYP2D6.92 produced truncated proteins of 25 KD exhibited a significantly reduced protein expression level compared with that of the wild-type enzyme CYP2D6.1; no p-value given. *92 construct contains 218 frameshift.
专家论述
CYP2D6 *92 is associated with decreased expression of CYP2D6 in insect cell microsomes as compared to CYP2D6 *1.