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记事
The 3' UTR of SLC22A3 was cloned into an expression vector and 11 SNPs were introduced into the 3' UTR. The vector was introduced into various cell lines (HCT-116, HepG2, DU145, A549) and their effect on gene expression was measured by luciferase assay. Data represent mean 卤 S.D., n = 3 replicates per cell line
专家论述
Allele G is associated with decreased expression of SLC22A3 as compared to allele C.