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记事
Enhancer SNPs (rs5758550/rs133333 - in LD) were associated with a 2-fold increase in CYP2D6 mRNA levels (P = 0.036) in a multiple linear regression analyses adjusted for s16947 genotype.
专家论述
Genotypes AG + GG are associated with increased expression of CYP2D6 in human liver cells as compared to genotype AA.