当前位置：药药网 / 数据中心 /变体注释摘要_体外和功能分析类型
巯基嘌呤-mercaptopurine
变量_单倍型
TPMT*1, TPMT*9, TPMT*21, TPMT*24, TPMT*25
记事
Five people with intermediate TPMT activity phenotype had the entire TPMT coding region and the 5'-flanking promoter region sequenced. One carried the *9 allele, one carried *21, one carried *24 and two carried *25.
专家论述
TPMT *1/*9 + *1/*21 + *1/*24 + *1/*25 are associated with decreased activity of TPMT when assayed with mercaptopurine in red blood cells as compared to TPMT *1/*1.
等位基因
*1/*9 + *1/*21 + *1/*24 + *1/*25