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苯妥英钠-mephenytoin
变量_单倍型
CYP2C19*1, CYP2C19*23
记事
The association is reported in comparison to *1B. Please note the study separates *1A and *1B. An increased Vmax was found for *23 compared to *1B (7.53 compared to 4.54). Vmax for *1A was 5.26.
专家论述
CYP2C19 *23 is associated with increased catalytic activity of CYP2C19 when exposed to mephenytoin in cos-7 cells as compared to CYP2C19 *1.