当前位置：药药网 / 数据中心 /变体注释摘要_体外和功能分析类型
布呋洛尔-bufuralol
变量_单倍型
CYP2D6*1, CYP2D6*10
记事
Bufuralol 1 鈥?hydroxylation assays were performed with cell homogenates corresponding to 1.2 mg of protein. Construct expressing *10 P34S showed a decreased OH- bufuralol formation, whole *36 showed no formation.
专家论述
CYP2D6 *10 is associated with decreased catalytic activity of CYP2D6 when exposed to bufuralol in COS-1 cells as compared to CYP2D6 *1.