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美沙酮-methadone
记事
Insect microsomes expressing the CYP2C19 alleles were incubated with 50-2000碌M methadone. No information about the constructs other than the protein change (name of the variant) or cDNA *1 reference of wt. Relative intrinsic clearance for R125G was 35.53% of *1
专家论述
Allele G is associated with decreased clearance of methadone as compared to allele C.