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巯基嘌呤-mercaptopurine
变量_单倍型
TPMT*1, TPMT*2, TPMT*3A, TPMT*3B, TPMT*3C, TPMT*5, TPMT*6, TPMT*8, TPMT*10, TPMT*11, TPMT*12, TPMT*13
记事
Alleles grouped by PharmGKB
专家论述
TPMT *2 + *3A + *3B + *3C + *5 + *6 + *8 + *10 + *11 + *12 + *13 are associated with decreased enzyme activity of TPMT when assayed with mercaptopurine in COS-1 cells as compared to TPMT *1.
等位基因
*2 + *3A + *3B + *3C + *5 + *6 + *8 + *10 + *11 + *12 + *13