当前位置：药药网 / 数据中心 /变体注释摘要_体外和功能分析类型
巯基嘌呤-mercaptopurine
变量_单倍型
TPMT*1, TPMT*2, TPMT*3A, TPMT*3C
记事
Genotyping was performed to detect *2,*3A,*3B, and *3C alleles. All subjects in the high activity group were typed as *1/*1. 26 out of 30 intermediate phenotype subjects were carriers of one of these other alleles.
专家论述
TPMT *1/*2 + *1/*3A + *1/*3C is associated with decreased enzyme activity of TPMT when assayed with mercaptopurine in red blood cells as compared to TPMT *1/*1.
等位基因
*1/*2 + *1/*3A + *1/*3C