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巯基嘌呤-mercaptopurine
变量_单倍型
TPMT*1, TPMT*3A, TPMT*3C
记事
Genotyping was performed to detect *2,*3A,*3B, and *3C alleles. All subjects in the high activity group were typed as *1/*1.
专家论述
TPMT *3A/*3C is associated with decreased enzyme activity of TPMT when assayed with mercaptopurine in red blood cells as compared to TPMT *1/*1.