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endoxifen-endoxifen
记事
Sensitivity to endoxifen was assayed by dose dependent growth inhibition in vitro of cells administered increasing doses of endoxifen. The authors reported that 141 unique associations between SNPs, miRNA, mRNA expression that were significantly related to endoxifen sensitivity. Only rs4386686 was explicitly described in the paper.
专家论述
Allele C is associated with increased sensitivity to endoxifen HapMal LCLs as compared to allele G.