当前位置：药药网 / 数据中心 /变体注释摘要_表型的关联,无论是否使用药物
咖啡因-caffeine
记事
In-vitro analysis for the variant as compared to wild type. Nucleotide change was introduced into rabbit RYR1 cDNA. The constructs expressed in HEK-293 cells and caffeine-induced calcium release was measured.
专家论述
Allele A is associated with increased sensitivity to caffeine in HEK-293 cells as compared to allele G.