注释ID

1296598626

变量_单倍型

rs104893684

基因

BCHE

药物名称(英)

药物名称(中)

PMID

25447891

类型

"Other","Metabolism/PK"

含义

not stated

记事

This SNP was associated with decreased enzyme activity of BCHE, which also corresponded with decreased inhibition with fluoride and dibucaine. It is found at a very high frequency in the Vysya community in Tamil Nadu, India. The alleles were not in HWE, which the authors attribute to high rates of consanguineous marriages. The mean BCHE enzyme activity for the TT, CT and CC genotypes was >10 U/ml, 2-10 U/ml, and <1 U/ml, respectively.

专家论述

Allele G is associated with decreased enzyme activity of BCHE as compared to allele A.

等位基因

G

专家评论

变体注释摘要

id	研究类型	特征类型
26798	cohort	Study Cohort