当前位置:药药网 / 数据中心 /变体注释摘要_表型的关联,无论是否使用药物
睾酮-testosterone
记事
Authors state " There was a moderate effect (22鈥?1% decrease) of the A337T mutation on 6-hydroxytestosterone and nifedipine oxidation (42% decrease)." Mapped using PharmVar.
专家论述
Allele T is associated with decreased enzyme activity of CYP3A5 when assayed with testosterone as compared to allele C.