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巯基嘌呤-mercaptopurine
记事
Authors stated "Although no statistically significant associations were identified, two of the four patients heterozygous for NUDT15 required a decrease in 6-MP during the follow-up period. " No TT homozygotes were observed. "Studies with a larger population size are needed"
专家论述
Genotype CT is associated with decreased dose of mercaptopurine in children with Precursor Cell Lymphoblastic Leukemia-Lymphoma as compared to genotype CC.